Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360966 | 0.85 | DPP4 (0.41) | DPP4CYP2D6DYRK1A | |
| SCHEMBL3363973 | 0.82 | DPP4 (0.43) | DPP4PRMT5WDR77ATM | |
| SCHEMBL3361880 | 0.79 | DPP4 (0.47) | DPP4PDE10APRMT5WDR77 | |
| SCHEMBL3365213 | 0.78 | DPP4 (0.47) | DPP4CYP2D6PRMT5WDR77 | |
| SCHEMBL3361992 | 0.78 | DPP4 (0.50) | DPP4PDE10A | |
| SCHEMBL3362196 | 0.75 | DPP4 (0.46) | DPP4PDE10A | |
| SCHEMBL3361923 | 0.75 | DPP4 (0.64) | DPP4 | |
| SCHEMBL3361990 | 0.75 | DPP4 (0.44) | DPP4PRMT5WDR77KDM4E | |
| SCHEMBL3362189 | 0.75 | DPP4 (0.43) | DPP4PDE10AATMKDM4E | |
| SCHEMBL3361983 | 0.74 | DPP4 (0.56) | DPP4PDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |