Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366336 | 0.79 | BACE1 (0.51) | ATRBACE1ALOX5APFEN1PTPN1 | |
| SCHEMBL16702483 | 0.77 | ALOX5AP (0.58) | ATRBACE1ALOX5APFEN1MPL | |
| SCHEMBL2442229 | 0.75 | BACE1 (0.48) | ATRBACE1ALOX5APFEN1PTPN1 | |
| SCHEMBL3128136 | 0.75 | ATR (0.48) | ATRBACE1ALOX5APFEN1PTPN1 | |
| SCHEMBL2447801 | 0.74 | BACE1 (0.47) | BACE1ALOX5APFEN1PTPN1KMO | |
| SCHEMBL15268979 | 0.74 | ALOX5AP (0.55) | ATRALOX5APFEN1ALDH1A1HSD17B10 | |
| SCHEMBL3362503 | 0.74 | HSP90AA1 (0.50) | ATRBACE1ALOX5APFEN1PTPN1 | |
| SCHEMBL3366129 | 0.74 | ALOX5AP (0.45) | ATRBACE1ALOX5APFEN1PTPN1 | |
| SCHEMBL14879962 | 0.72 | CNR2 (0.51) | ATRBACE1ALOX5APFEN1PTPN1 | |
| SCHEMBL3093233 | 0.72 | DPP4 (0.47) | ATRBACE1ALOX5APFEN1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |