Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397662 | 0.81 | NOS3 (0.39) | ALOX5APFEN1NUDT1TLR8HSP90AA1 | |
| SCHEMBL16702483 | 0.78 | ALOX5AP (0.58) | ALOX5APFEN1IDO1ADORA2AATR | |
| SCHEMBL5142203 | 0.78 | IDO1 (0.44) | IDO1METAP2ADORA2AATP4AATP4B | |
| SCHEMBL3362503 | 0.78 | HSP90AA1 (0.50) | ALOX5APFEN1IDO1ADORA2AATP4A | |
| SCHEMBL15268979 | 0.78 | ALOX5AP (0.55) | ALOX5APFEN1ADORA2AATRGRM4 | |
| SCHEMBL23363523 | 0.77 | ATR (0.46) | ALOX5APFEN1ATRGRM4DHFR | |
| SCHEMBL3363101 | 0.77 | HSP90AA1 (0.53) | METAP2ADORA2AATP4AATP4BATR | |
| SCHEMBL29899259 | 0.77 | ATR (0.46) | ALOX5APFEN1ATRGRM4DHFR | |
| SCHEMBL3366206 | 0.77 | ASIC3 (0.53) | IDO1METAP2ADORA2AATP4AATP4B | |
| SCHEMBL10304960 | 0.75 | IDO1 (0.42) | IDO1METAP2ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |