Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23246118 | 0.86 | IDO1 (0.47) | IDO1CDK2ALOX5APFEN1PTPN1 | |
| SCHEMBL4693972 | 0.80 | GAA (0.47) | IDO1CDK2ALOX5APFEN1PIM1 | |
| SCHEMBL3366129 | 0.78 | ALOX5AP (0.45) | HSP90AA1IDO1ALOX5APFEN1ATP4A | |
| SCHEMBL18573250 | 0.78 | IDO1 (0.46) | HSP90AA1HSP90AB1IDO1PIM1PIM3 | |
| SCHEMBL16702483 | 0.78 | ALOX5AP (0.58) | IDO1ALOX5APFEN1MAPK14PIM1 | |
| SCHEMBL15268979 | 0.78 | ALOX5AP (0.55) | ALOX5APFEN1ATRALDH1A1HSD17B10 | |
| SCHEMBL1915309 | 0.77 | ASIC3 (0.53) | HSP90AA1HSP90AB1IDO1ATP4AATP4B | |
| SCHEMBL30251342 | 0.77 | ASIC3 (0.53) | HSP90AA1HSP90AB1IDO1ATP4AATP4B | |
| SCHEMBL3362241 | 0.74 | ATR (0.46) | ALOX5APFEN1ATRBACE1ALDH1A1 | |
| SCHEMBL3363101 | 0.74 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1ATP4AATP4BATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |