Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | AKT2 | P31751 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL3362977 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAPTNPC1RAB9AGAA | |
| SCHEMBL21239628 | 0.65 | NPC1 (0.33) | ALDH1A1MAPTNPC1RAB9AGAA | |
| Biphenyl SCHEMBL10535512 | 0.61 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9ABRD4BRD2 | |
| Biphenyl SCHEMBL3908169 | 0.60 | ALDH1A1 (0.69) | ALDH1A1MAPTAKT1AKT2KMT2A | |
| Biphenyl SCHEMBL6364305 | 0.60 | ALDH1A1 (0.69) | ALDH1A1NPC1RAB9AAKT1AKT2 | |
| Biphenyl SCHEMBL28881047 | 0.60 | ALDH1A1 (0.69) | ALDH1A1MAPTAKT1AKT2KMT2A | |
| Biphenyl SCHEMBL5586130 | 0.59 | ALDH1A1 (0.82) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| Biphenyl SCHEMBL388156 | 0.59 | ALDH1A1 (0.82) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| Biphenyl SCHEMBL653702 | 0.59 | ALDH1A1 (0.82) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| Biphenyl SCHEMBL164 | 0.59 | ALDH1A1 (1.00) | ALDH1A1MAPTNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034236-A1 | PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2010-04-01 | — | — | WO | disclosed |