Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | ELOC | Q15369 | 1/20 | 0.37 |
| ▸ | ELOB | Q15370 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5667423 | 0.82 | CA2 (0.52) | CA2CA4CA5ATSHRPGK1 | |
| SCHEMBL8385998 | 0.81 | CA2 (0.50) | CA2CA4CA5ATSHRCA12 | |
| SCHEMBL2171752 | 0.81 | CA2 (0.71) | CA2CA4CA5ATSHRGAA | |
| Diamidophosphate SCHEMBL10932540 | 0.79 | CA1 (0.50) | CA2CA4CA5ATSHRCA12 | |
| SCHEMBL2597582 | 0.78 | CA2 (0.48) | CA2CA4CA5ATSHRPGK1 | |
| SCHEMBL344618 | 0.78 | SMN1; SMN2 (0.52) | CA2CA4CA5ATSHRLMNA | |
| SCHEMBL13538144 | 0.78 | CA2 (0.48) | CA2CA4CA5ACA12CA1 | |
| SCHEMBL2208306 | 0.78 | TSHR (0.40) | CA2CA4CA5ATSHRCA12 | |
| Hydrochloric Acid SCHEMBL22165294 | 0.76 | CA2 (0.46) | CA2CA4CA5ACA12CA1 | |
| SCHEMBL3399311 | 0.76 | SMN1; SMN2 (0.50) | CA2CA4CA5ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107987235-A | A kind of preparation method of low hydration heat crack resistance type polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-107987228-A | A kind of preparation method of low hydration heat Early-strength polycarboxylate superplasticizer | 科之杰新材料集团有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-107987227-A | A kind of preparation method of low hydration heat extra retarded set type polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-107868187-A | A kind of preparation method of low hydration heat polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-04-03 | — | — | CN | claimed |
| US-20230352250-A1 | PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTRIC CONVERSION MODULE, ELECTRONIC DEVICE, AND POWER SUPPLY MODULE | RICOH COMPANY, LTD. (JP) | 2023-11-02 | — | — | US | disclosed |
| CN-107987228-A | A kind of preparation method of low hydration heat Early-strength polycarboxylate superplasticizer | 科之杰新材料集团有限公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-107987235-A | A kind of preparation method of low hydration heat crack resistance type polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-107987227-A | A kind of preparation method of low hydration heat extra retarded set type polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-107868187-A | A kind of preparation method of low hydration heat polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-04-03 | — | — | CN | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| CN-101591281-A | Phosphonate compounds having immunomodulatory activity | GILEAD SCIENCES INC (US) | 2009-12-02 | — | — | CN | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | GILEAD SCIENCES. INC. | 2005-10-27 | — | — | US | disclosed |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. | 2005-09-22 | — | — | US | disclosed |
| WO-2005064008-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| EP-1509537-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003090690-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | PPA1, PPME1, PNP | CA2 3935/4885CA4 3269/4885CA5A 3294/4885 |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | CES1, PNP, PGLS | CA2 3487/4885CA4 1030/4885CA5A 2188/4885 |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | CA2 3915/4885CA4 3211/4885CA5A 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.