Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362932 | 0.79 | PLK1 (0.41) | KIF11MGLLMEN1KMT2ATP53 | |
| SCHEMBL18242556 | 0.74 | MGLL (0.47) | KIF11MGLLTP53BCL2HTR2A | |
| SCHEMBL9153494 | 0.73 | KIF11 (0.40) | KIF11MGLLMEN1KMT2ATP53 | |
| Propionaldehyde SCHEMBL27907303 | 0.73 | TP53 (0.46) | MGLLTP53BCL2CYP1A2CYP2A6 | |
| SCHEMBL5971259 | 0.73 | KIF11 (0.53) | KIF11MGLLTP53HTR2AHTR2B | |
| SCHEMBL30573009 | 0.73 | KIF11 (0.49) | KIF11MGLLTP53HTR2AHTR2B | |
| SCHEMBL1653927 | 0.73 | KIF11 (0.49) | KIF11MGLLTP53HTR2AHTR2B | |
| SCHEMBL16105424 | 0.73 | KIF11 (0.49) | KIF11MGLLTP53BCL2HTR2A | |
| Formic Acid SCHEMBL27266665 | 0.73 | BCL2 (0.47) | MGLLMEN1KMT2ATP53BCL2 | |
| SCHEMBL3362928 | 0.72 | KCNN4 (0.48) | KIF11CYP1A2NPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |