Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361280 | 0.79 | CES2 (0.47) | NFE2L2CES2MAPK1RAB9AFBP1 | |
| SCHEMBL5643430 | 0.78 | KCNN4 (0.47) | KCNN4PTPN1NFE2L2CYP19A1KIF11 | |
| SCHEMBL3362675 | 0.75 | CYP19A1 (0.40) | CYP19A1KIF11CYP1A2CHRM5PARP1 | |
| SCHEMBL3364629 | 0.75 | KCNN4 (0.43) | KCNN4PTPN1CYP19A1CES2CES1 | |
| SCHEMBL3361991 | 0.73 | PTPN1 (0.50) | PTPN1KIF11 | |
| SCHEMBL27497591 | 0.73 | KCNN4 (0.47) | KCNN4PTPN1CES2MTORMAPK1 | |
| SCHEMBL248378 | 0.73 | KCNN4 (0.50) | KCNN4PTPN1NFE2L2CYP19A1KIF11 | |
| SCHEMBL308018 | 0.73 | NFE2L2 (0.46) | KCNN4PTPN1NFE2L2CES2CES1 | |
| Bromide SCHEMBL7180638 | 0.72 | CYP19A1 (0.39) | KCNN4PTPN1NFE2L2CYP19A1KIF11 | |
| SCHEMBL3362950 | 0.72 | KIF11 (0.42) | KIF11CYP1A2MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |