SCHEMBL3363142

SCHEMBL3363142

CC(=O)OC(CC1CC2C=CC1C2)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.35
ALDH1A1 P00352 5/20 0.34
TDP1 Q9NUW8 3/20 0.34
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33
PKM P14618 3/20 0.31
MAPT P10636 2/20 0.31
MAPK1 P28482 1/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6423573 0.87 KDM4E (0.38) KDM4EALDH1A1TDP1POLBALOX15
SCHEMBL24355008 0.86 KDM4E (0.34) KDM4EALDH1A1TDP1POLBALOX15
SCHEMBL3364020 0.85 KDM4E (0.33) KDM4EALDH1A1TDP1POLBALOX15
SCHEMBL3364410 0.84 KDM4E (0.34) KDM4EALDH1A1TDP1POLBALOX15
SCHEMBL3362486 0.80 KDM4E (0.38) KDM4EALDH1A1TDP1POLBALOX15
SCHEMBL12460485 0.79 KDM4E (0.32) KDM4EALDH1A1TDP1POLBALOX15
SCHEMBL14468756 0.79 KDM4E (0.36) KDM4EALDH1A1TDP1POLBALOX15
SCHEMBL14468501 0.79 KDM4E (0.36) KDM4EALDH1A1TDP1POLBALOX15
SCHEMBL15492228 0.77 KDM4E (0.35) KDM4EALDH1A1TDP1MEN1CYP1A2
SCHEMBL10300866 0.75 KDM4E (0.35) KDM4EALDH1A1MEN1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2045280-B1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF MITSUI CHEMICALS INC (JP) 2018-10-10 EP disclosed
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
EP-1164434-B1 Radiation-sensitive resin composition JSR CORP (JP) 2010-10-06 EP disclosed
US-7714079-B2 Ultra-large scale integrated (ULSI); film stack; hydrosilation INTERNATIONAL BUSINESS MACHINES CORPORAITON (US) 2010-05-11 US disclosed
US-7714079-B2 Ultra-large scale integrated (ULSI); film stack; hydrosilation INTERNATIONAL BUSINESS MACHINES CORPORAITON (US) 2010-05-11 US disclosed
US-7651829-B2 Positive resist material and pattern formation method using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-01-26 US disclosed
US-7651829-B2 Positive resist material and pattern formation method using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-01-26 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed
US-20080063880-A1 Ultra-large scale integrated (ULSI); film stack; hydrosilation INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-03-13 US disclosed
US-6933094-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-08-23 US disclosed
US-20040241580-A1 Radiation-sensitive resin composition NISHIMURA YUKIO (JP) 2004-12-02 US disclosed
US-6800414-B2 FLUOROPOLYMER JSR CORPORATION (JP) 2004-10-05 US disclosed
US-6623907-B2 Chemical amplified photoresist JSR CORPORATION (JP) 2003-09-23 US disclosed
US-20020058201-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-05-16 US disclosed
EP-1193558-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-04-03 EP disclosed
US-20020009668-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-01-24 US disclosed
EP-1164434-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-19 EP disclosed
US-20010023050-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2001-09-20 US disclosed
EP-1122605-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2001-08-08 EP disclosed