Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22482055 | 0.84 | PGK1 (0.43) | PGK1PGK2 | |
| SCHEMBL13680820 | 0.80 | CYP3A4 (0.39) | CYP3A4TSHRALDH1A1GAAMAPT | |
| Formic Acid SCHEMBL28289297 | 0.80 | CYP3A4 (0.36) | CYP3A4TSHRALDH1A1GAAMAPT | |
| SCHEMBL11495887 | 0.76 | CYP3A4 (0.35) | CYP3A4TSHRALDH1A1GAAMAPT | |
| SCHEMBL7052424 | 0.76 | — | — | |
| SCHEMBL247492 | 0.75 | SMN1; SMN2 (0.44) | CYP3A4TSHRALDH1A1HPGDMBOAT4 | |
| SCHEMBL20400755 | 0.75 | CCR1 (0.40) | PGK1PGK2 | |
| SCHEMBL20730061 | 0.75 | PGK1 (0.41) | PGK1PGK2 | |
| SCHEMBL4287573 | 0.75 | MBOAT4 (0.33) | MBOAT4PGK1PGK2 | |
| SCHEMBL6745 | 0.75 | PARP1 (0.38) | ALDH1A1HPGDMBOAT4PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514802-A1 | IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023208986-A1 | IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-11-02 | — | — | WO | disclosed |
| WO-2018055578-A1 | PREVENTIVE AND THERAPEUTIC APPROACH FOR ABERRANT CELL DIFFERENTIATION AND ISR-ASSOCIATED DISEASES | THE UNIVERSITY OF HONG KONG (CN) | 2018-03-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |