Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360993 | 0.92 | LMNA (0.39) | LMNA | |
| SCHEMBL27601257 | 0.91 | LMNA (0.55) | LMNA | |
| SCHEMBL399581 | 0.86 | LMNA (0.50) | LMNA | |
| SCHEMBL20478196 | 0.86 | LMNA (0.50) | LMNA | |
| SCHEMBL314440 | 0.86 | LMNA (0.50) | LMNA | |
| SCHEMBL3792627 | 0.86 | LMNA (0.50) | LMNA | |
| SCHEMBL3741069 | 0.86 | LMNA (0.50) | LMNA | |
| SCHEMBL20478198 | 0.86 | LMNA (0.50) | LMNA | |
| SCHEMBL6009511 | 0.86 | LMNA (0.50) | LMNA | |
| SCHEMBL396922 | 0.86 | LMNA (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121710-A1 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INCORPORATED (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2008106132-A9 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INC (US) | 2009-06-18 | — | — | WO | claimed |
| WO-2008106132-A1 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INCORPORATED (US) | 2008-09-04 | — | — | WO | claimed |
| US-20080207937-A1 | Asymmetric bis-silanes and methods for making and their use | CORNING INCORPORATED | 2008-08-28 | — | — | US | claimed |
| US-7671227-B2 | Asymmetric bis-silanes and methods for making and their use | CORNING INCORPORATED (US) | 2010-03-02 | — | — | US | disclosed |
| US-7671227-B2 | Asymmetric bis-silanes and methods for making and their use | CORNING INCORPORATED (US) | 2010-03-02 | — | — | US | disclosed |
| EP-2121710-A1 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INCORPORATED (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008106132-A9 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INC (US) | 2009-06-18 | — | — | WO | disclosed |
| WO-2008106132-A1 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INCORPORATED (US) | 2008-09-04 | — | — | WO | disclosed |
| US-20080207937-A1 | Asymmetric bis-silanes and methods for making and their use | CORNING INCORPORATED | 2008-08-28 | — | — | US | disclosed |
| US-20080207937-A1 | Asymmetric bis-silanes and methods for making and their use | CORNING INCORPORATED | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207937-A1 | Asymmetric bis-silanes and methods for making and their use | SIN3A, SPIN3, SUDS3 | LMNA 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.