SCHEMBL3363407

SCHEMBL3363407

C=CCOC[C@H](CO)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
CA1 P00915 5/20 0.37
CA2 P00918 3/20 0.37
CA7 P43166 3/20 0.37
CA9 Q16790 2/20 0.37
TSHR P16473 1/20 0.37
SLC1A3 P43003 2/20 0.36
SLC1A2 P43004 2/20 0.36
SLC1A1 P43005 2/20 0.36
CYP2D6 P10635 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
TACR1 P25103 2/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8007515 1.00 ALOX15 (0.38) ALOX15CA1CA2CA7CA9
SCHEMBL3286596 1.00 ALOX15 (0.38) ALOX15CA1CA2CA7CA9
SCHEMBL29342865 0.97 ALOX15 (0.36) ALOX15CA1CA2CA7CA9
SCHEMBL29343105 0.97 ALOX15 (0.36) ALOX15CA1CA2CA7CA9
SCHEMBL24933005 0.88 CA1 (0.44) ALOX15CA1CA2CA7CA9
SCHEMBL30876749 0.86 TDP1 (0.39) ALOX15CA1CA2CA7CA9
SCHEMBL11195121 0.85 ALOX15 (0.38) ALOX15CA1CA2CA7CA9
SCHEMBL8904530 0.84 CA1 (0.51) CA1CA2CA7CA9TSHR
SCHEMBL19043237 0.84 TSHR (0.45) CA1CA2CA7CA9TSHR
SCHEMBL828589 0.84 CA1 (0.51) CA1CA2CA7CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076520-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2011-12-13 US disclosed
US-20100280282-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2010-11-04 US disclosed
US-7709464-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E. V. (DE) 2010-05-04 US disclosed
US-20090035358-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2009-02-05 US disclosed
US-7351428-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2008-04-01 US disclosed
US-20040213836-A1 Phosphatidyl oligoglycerols MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2004-10-28 US disclosed
US-20030053978-A1 Phosphatidyl oligoglycerols MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. 2003-03-20 US disclosed
US-20020090383-A1 Compounds which increase the survival duration of liposomes MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2002-07-11 US disclosed
US-6413543-B1 DRUG DELIVERY MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2002-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040213836-A1 Phosphatidyl oligoglycerols PHOSPHO1, SGMS1, SGMS2 ALOX15 423/4885CA1 3928/4885CA2 4024/4885
US-20030053978-A1 Phosphatidyl oligoglycerols PHOSPHO1, SGMS1, SGMS2 ALOX15 411/4885CA1 4298/4885CA2 3994/4885
US-20020090383-A1 Compounds which increase the survival duration of liposomes VEGFA, MCL1, LIPA ALOX15 589/4885CA1 2013/4885CA2 3532/4885
US-20100280282-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG ALOX15 508/4885CA1 4665/4885CA2 4175/4885
US-20090035358-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG ALOX15 508/4885CA1 4665/4885CA2 4175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.