Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366055 | 0.81 | NOS3 (0.52) | MAPK14KDM4EMEN1NOS3NOS1 | |
| SCHEMBL22426647 | 0.81 | PDK2 (0.47) | CTSDBACE1LCKKDRJAK3 | |
| SCHEMBL972623 | 0.80 | MKNK1 (0.49) | KDM4EMEN1NOS3NOS1NOS2 | |
| SCHEMBL7709062 | 0.79 | BACE1 (0.57) | CTSDBACE1LCKKDRJAK3 | |
| SCHEMBL5254154 | 0.78 | PIK3CD (0.44) | CTSDBACE1KDM4EMEN1NOS3 | |
| SCHEMBL3362961 | 0.78 | PIK3C3 (0.61) | BACE1JAK3ALOX5APFEN1DYRK1A | |
| SCHEMBL4928287 | 0.78 | IDO1 (0.44) | CTSDBACE1LCKKDRJAK3 | |
| SCHEMBL3361169 | 0.77 | DYRK1A (0.60) | ALOX5APFEN1NOS3NOS1NOS2 | |
| SCHEMBL21859672 | 0.77 | ABL1 (0.62) | BACE1MAPK14KDM4EMEN1NOS3 | |
| SCHEMBL30091450 | 0.77 | ABL1 (0.62) | BACE1MAPK14KDM4EMEN1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |