Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897390 | 0.79 | TSHR (0.50) | BACE1CTSDLCKKDRJAK3 | |
| SCHEMBL28233418 | 0.79 | HSP90AA1 (0.54) | BACE1CTSDLCKKDRJAK3 | |
| SCHEMBL3363667 | 0.79 | CTSD (0.53) | BACE1CTSDLCKKDRJAK3 | |
| SCHEMBL19539213 | 0.78 | TRPA1 (0.47) | BACE1CTSDLCKKDRJAK3 | |
| SCHEMBL28247998 | 0.77 | CTSD (0.47) | BACE1CTSDLCKKDRJAK3 | |
| SCHEMBL13483636 | 0.77 | TRPA1 (0.46) | BACE1CTSDLCKKDRJAK3 | |
| SCHEMBL7702897 | 0.75 | BACE1 (0.57) | BACE1JAK3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7708786 | 0.75 | BACE1 (0.57) | BACE1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7711745 | 0.75 | HSD17B10 (0.54) | SMN1; SMN2KDM4EHSD17B10ALOX5APFEN1 | |
| SCHEMBL30488032 | 0.75 | NUDT1 (0.50) | BACE1CTSDLCKKDRJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |