Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363791 | 1.00 | MLYCD (0.52) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL3364258 | 0.87 | L3MBTL1 (0.57) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL3364252 | 0.87 | L3MBTL1 (0.57) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL3882782 | 0.84 | MLYCD (0.56) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL13103578 | 0.84 | MLYCD (0.59) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL2749290 | 0.83 | MLYCD (0.55) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL6173159 | 0.82 | HTR2A (0.57) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL5016361 | 0.81 | MLYCD (0.55) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL12310890 | 0.80 | HTR2A (0.55) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL15682777 | 0.80 | NPC1 (0.59) | MLYCDMEN1KMT2APLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | GRUENENTHAL GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | KCNQ1, KCNQ3, KCNQ2 | MLYCD 4649/4885MEN1 1348/4885KMT2A 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.