Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364252 | 1.00 | L3MBTL1 (0.57) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL3363791 | 0.87 | MLYCD (0.52) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL3363787 | 0.87 | MLYCD (0.52) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL3882782 | 0.86 | MLYCD (0.56) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL13103578 | 0.86 | MLYCD (0.59) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL5016361 | 0.85 | MLYCD (0.55) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL6173159 | 0.84 | HTR2A (0.57) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL3369040 | 0.84 | TACR1 (0.58) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL12310890 | 0.82 | HTR2A (0.55) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B | |
| SCHEMBL2749290 | 0.80 | MLYCD (0.55) | L3MBTL1MLYCDKMT2AMEN1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | GRUENENTHAL GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | KCNQ1, KCNQ3, KCNQ2 | L3MBTL1 2790/4885MLYCD 4649/4885KMT2A 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.