Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365615 | 0.92 | DPP4 (0.41) | DPP4GAAHTTMEN1KMT2A | |
| SCHEMBL3361319 | 0.88 | GAA (0.44) | CLK1CYP3A4RECQLGAAHTT | |
| SCHEMBL3363205 | 0.84 | DPP4 (0.56) | CLK1TLR9TLR8TLR7RECQL | |
| Hydrochloric Acid SCHEMBL3366027 | 0.83 | DPP4 (0.56) | CLK1TLR9TLR8TLR7RECQL | |
| SCHEMBL3363213 | 0.82 | TLR8 (0.40) | TLR9TLR8TLR7DPP4GAA | |
| SCHEMBL3361777 | 0.82 | TP53 (0.41) | DPP4TSHRMEN1KMT2AMAPT | |
| SCHEMBL3363088 | 0.80 | DPP4 (0.41) | DPP4MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL3363099 | 0.79 | DPP4 (0.49) | DPP4GAACYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL7716634 | 0.79 | ABCC1 (0.38) | DPP4GAAHTTTSHRMEN1 | |
| SCHEMBL3361175 | 0.79 | HPGD (0.44) | DPP4GAAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |