Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362101 | 0.88 | DPP4 (0.67) | DPP4GAASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL3361298 | 0.87 | DPP4 (0.46) | DPP4ABCB1HSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL3362437 | 0.86 | DPP4 (0.45) | DPP4ABCB1GFERHSD17B10L3MBTL1 | |
| SCHEMBL3361307 | 0.86 | DPP4 (0.46) | DPP4ABCB1GFERHSD17B10L3MBTL1 | |
| SCHEMBL3365202 | 0.86 | DPP4 (0.44) | DPP4HSD17B10L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL3365615 | 0.84 | DPP4 (0.41) | DPP4L3MBTL1DYRK1AGAAALDH1A1 | |
| SCHEMBL3365213 | 0.84 | DPP4 (0.47) | DPP4CTSL | |
| SCHEMBL3363088 | 0.83 | DPP4 (0.41) | DPP4ABCB1GFERHSD17B10L3MBTL1 | |
| SCHEMBL3359830 | 0.83 | NAMPT (0.44) | DPP4GFERHSD17B10L3MBTL1GAA | |
| SCHEMBL3362011 | 0.82 | DPP4 (0.40) | DPP4ABCB1GFERHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |