Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361319 | 0.92 | GAA (0.44) | HTTSMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL3366103 | 0.91 | TSHR (0.40) | CTSLCTSBCTSSPTPN1HTT | |
| SCHEMBL3362011 | 0.88 | DPP4 (0.40) | CTSLCKS1BSKP1SKP2TSHR | |
| SCHEMBL3361886 | 0.88 | DPP4 (0.41) | ABCC1CTSLCTSBCTSSCKS1B | |
| SCHEMBL3365615 | 0.87 | DPP4 (0.41) | CTSLCTSBCTSSPTPN1HTT | |
| SCHEMBL7720962 | 0.85 | DPP4 (0.49) | ABCC1HTTTSHRALOX15SMN1; SMN2 | |
| SCHEMBL7723483 | 0.83 | GAA (0.40) | HTTTSHRSMN1; SMN2GAAMEN1 | |
| SCHEMBL3361777 | 0.80 | TP53 (0.41) | CKS1BSKP1SKP2TSHRMEN1 | |
| SCHEMBL3360962 | 0.80 | DPP4 (0.41) | GAAKMT2ADPP4 | |
| SCHEMBL3363987 | 0.79 | CLK1 (0.42) | HTTTSHRSMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |