Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363987 | 0.92 | CLK1 (0.42) | DPP4GAAHTTMEN1KMT2A | |
| SCHEMBL3361777 | 0.90 | TP53 (0.41) | DPP4HPGDMEN1KMT2AROCK2 | |
| SCHEMBL3361175 | 0.87 | HPGD (0.44) | DPP4GAAHPGDHTTMEN1 | |
| SCHEMBL7716634 | 0.87 | ABCC1 (0.38) | DPP4GAAHTTMEN1KMT2A | |
| SCHEMBL3363088 | 0.86 | DPP4 (0.41) | DPP4MEN1KMT2ACTSSPTPN1 | |
| SCHEMBL3363213 | 0.85 | TLR8 (0.40) | DPP4GAAMEN1KMT2AKDM4E | |
| SCHEMBL3363099 | 0.84 | DPP4 (0.49) | DPP4GAACTSLPTPN1ALDH1A1 | |
| SCHEMBL3363889 | 0.83 | DPP4 (0.59) | DPP4GAAHPGDHTTMEN1 | |
| SCHEMBL3361307 | 0.82 | DPP4 (0.46) | DPP4CTSLALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL3366103 | 0.81 | TSHR (0.40) | DPP4GAAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |