Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972004 | 0.86 | NPC1 (0.35) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL13039618 | 0.75 | NPC1 (0.41) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL3340050 | 0.75 | NPC1 (0.40) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL10970812 | 0.74 | NPC1 (0.42) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL10974043 | 0.72 | NPC1 (0.46) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL15684095 | 0.72 | NPC1 (0.46) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL10973763 | 0.70 | NPC1 (0.61) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL24359191 | 0.70 | ALDH1A1 (0.36) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL5227279 | 0.70 | NPC1 (0.33) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL23932135 | 0.70 | KMT2A (0.43) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045379-A2 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2010-04-22 | — | — | WO | disclosed |