Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 17/20 | 0.65 |
| ▸ | DDO | Q99489 | 5/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360987 | 0.83 | DAO (0.61) | DAODDO | |
| SCHEMBL3363264 | 0.83 | DAO (0.61) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3435254 | 0.83 | DAO (0.61) | DAODDO | |
| SCHEMBL16767858 | 0.79 | DAO (1.00) | DAODDO | |
| SCHEMBL15515566 | 0.71 | HPGD (0.56) | DAOGRIN1 | |
| SCHEMBL25903828 | 0.71 | CA12 (0.62) | — | |
| SCHEMBL26912440 | 0.70 | CCNC (0.40) | — | |
| SCHEMBL3360150 | 0.70 | DAO (0.59) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9389378 | 0.70 | DAO (0.50) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5673136 | 0.69 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |