SCHEMBL3435254

SCHEMBL3435254

O=c1[nH]c2c(F)c(Cl)ccc2cc1O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DAO P14920 19/20 0.61
DDO Q99489 7/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3364081 0.83 DAO (0.65) DAODDO
SCHEMBL3363264 0.80 DAO (0.61) DAODDO
SCHEMBL3360987 0.80 DAO (0.61) DAODDO
SCHEMBL3360565 0.76 DAO (0.53) DAODDO
SCHEMBL16767858 0.76 DAO (1.00) DAODDO
SCHEMBL3360150 0.75 DAO (0.59) DAODDO
SCHEMBL3432869 0.74 DAO (0.58) DAODDO
SCHEMBL7677228 0.73 EIF4A3 (0.61) DAO
SCHEMBL3360159 0.73 DAO (0.58) DAODDO
SCHEMBL3395093 0.73 DAO (0.67) DAODDO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010058314-A1 HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF PFIZER INC. (US) 2010-05-27 WO disclosed