SCHEMBL3364276

SCHEMBL3364276

CCOC(=O)Oc1ccccc1C(=O)C(O)c1cc(OC)cc(OC)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.42
KDM4E B2RXH2 3/20 0.42
HSD17B10 Q99714 2/20 0.42
KMT2A Q03164 5/20 0.38
TSHR P16473 4/20 0.38
MEN1 O00255 4/20 0.38
CDC25B P30305 1/20 0.38
MAPT P10636 4/20 0.37
L3MBTL1 Q9Y468 4/20 0.37
LMNA P02545 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
GAA P10253 1/20 0.37
POLB P06746 2/20 0.37
PLIN1 O60240 1/20 0.37
PLIN5 Q00G26 1/20 0.37
ABHD5 Q8WTS1 1/20 0.37
TDP1 Q9NUW8 4/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPK1 P28482 2/20 0.37
ATM Q13315 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29210396 0.84 HPGD (0.43) HPGDKDM4EHSD17B10KMT2ATSHR
SCHEMBL3364576 0.75 CES2 (0.47) KDM4EKMT2ATSHRMEN1MAPT
SCHEMBL4391331 0.72 SLC6A3 (0.59) HPGDKDM4EHSD17B10KMT2ATSHR
SCHEMBL1873260 0.72 KDM4E (0.67) HPGDKDM4EHSD17B10KMT2ATSHR
SCHEMBL4391361 0.72 TSHR (0.67) HPGDKDM4EHSD17B10KMT2ATSHR
SCHEMBL11925423 0.71 KDM4E (0.56) HPGDKDM4EHSD17B10KMT2ATSHR
SCHEMBL6890110 0.71 MAPT (0.51) KDM4EKMT2ATSHRMEN1MAPT
SCHEMBL8516383 0.71 TSHR (0.52) HPGDKDM4EHSD17B10KMT2ATSHR
SCHEMBL1914150 0.70 TSHR (0.55) HPGDKDM4EHSD17B10KMT2ATSHR
SCHEMBL1913945 0.70 TSHR (0.50) HPGDKDM4EHSD17B10KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1617812-B1 PHOTORESPONSIVE FRAGRANCES PHO DERMA INC (US) 2010-10-06 EP disclosed
EP-1021159-B1 PHOTORESPONSIVE SUNSCREEN COMPOSITIONS CALIFORNIA INST OF TECHN (US) 2006-07-12 EP disclosed
EP-1617812-A2 PHOTORESPONSIVE FRAGRANCES Pho Derma, Inc. (US) 2006-01-25 EP disclosed
US-20050020459-A1 Carrier solution for cleaning purposes or topical applying SOLARBRE, INC. 2005-01-27 US disclosed
WO-2004084853-A2 PHOTORESPONSIVE FRAGRANCES PHO DERMA, INC. (US) 2004-10-07 WO disclosed
US-6280711-B1 INTRAMOLECULAR PHOTOCHEMICAL REARRANGEMENTS INDUCED BY ULTRAVIOLET RADIATION; TOPICAL CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-08-28 US disclosed
EP-1021159-A1 PHOTORESPONSIVE SUNSCREEN COMPOSITIONS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-07-26 EP disclosed
US-6022529-A Photoresponsive sunscreen compositions CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-08 US disclosed
WO-1999007336-A1 PHOTORESPONSIVE SUNSCREEN COMPOSITIONS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1999-02-18 WO disclosed