Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364276 | 0.84 | HPGD (0.42) | HPGDKDM4EHSD17B10HTTNPC1 | |
| SCHEMBL124171 | 0.82 | LMNA (0.52) | HPGDKDM4EHSD17B10TSHRMEN1 | |
| SCHEMBL139044 | 0.78 | CES2 (0.59) | KDM4EHTTNPC1RAB9ASMN1; SMN2 | |
| Bicarbonate SCHEMBL291493 | 0.77 | CES2 (0.58) | KDM4EHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL277654 | 0.76 | HPGD (0.56) | HPGDKDM4EHSD17B10HTTNPC1 | |
| Acetic Acid SCHEMBL3368380 | 0.76 | CES2 (0.56) | KDM4EHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10353077 | 0.75 | GAA (0.49) | KDM4EHTTNPC1RAB9ASMN1; SMN2 | |
| Methoxymethane SCHEMBL5593577 | 0.75 | HPGD (0.55) | HPGDKDM4EHSD17B10HTTNPC1 | |
| SCHEMBL126209 | 0.75 | KMT2A (0.44) | HPGDKDM4EHSD17B10HTTNPC1 | |
| Carbamic Acid SCHEMBL1695357 | 0.74 | CES2 (0.54) | KDM4EHTTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050647-A1 | IONIZABLE CATIONIC LIPID COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 晟迪生物医药(苏州)有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |