Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 7/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425430 | 0.82 | MAP3K14 (0.59) | EGLN2CYP11B1CYP11B2MAP3K14SCN9A | |
| SCHEMBL446276 | 0.80 | PIK3CA (0.43) | MAP3K14SCN9A | |
| SCHEMBL3361910 | 0.75 | CYP11B2 (0.42) | EGLN2CYP11B1CYP11B2SCN9AKCNH2 | |
| SCHEMBL30337173 | 0.75 | EGFR (0.43) | EGLN2MAP3K14SCN9A | |
| SCHEMBL3393269 | 0.75 | EGLN2 (0.41) | EGLN2MAP3K14SCN9AKCNH2S1PR1 | |
| SCHEMBL17542577 | 0.75 | EGFR (0.43) | EGLN2MAP3K14SCN9A | |
| SCHEMBL4378433 | 0.74 | MEN1 (0.48) | EGLN2CYP11B2 | |
| SCHEMBL3364557 | 0.74 | CSNK1A1 (0.43) | EGLN2CYP11B1CYP11B2SCN9AKCNH2 | |
| SCHEMBL24791485 | 0.74 | KCNH2 (0.53) | EGLN2KCNH2 | |
| SCHEMBL30872068 | 0.74 | KCNH2 (0.53) | EGLN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |