Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 6/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361910 | 0.87 | CYP11B2 (0.42) | CYP11B2CYP11B1EGLN2S1PR1SCN9A | |
| SCHEMBL3361914 | 0.83 | ADORA2A (0.51) | CYP11B2CYP11B1EGLN2S1PR1SCN9A | |
| SCHEMBL3399428 | 0.82 | CYP11B1 (0.39) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL30037562 | 0.77 | PDK1 (0.41) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL25552036 | 0.77 | PDK1 (0.41) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL3364321 | 0.74 | EGLN2 (0.47) | CYP11B2CYP11B1EGLN2S1PR1SCN9A | |
| SCHEMBL3362493 | 0.74 | EGLN2 (0.44) | CYP11B2CYP11B1EGLN2S1PR1HSP90AB1 | |
| SCHEMBL17629890 | 0.72 | CYP11B2 (0.41) | CYP11B2CYP11B1EGLN2KCNH2 | |
| SCHEMBL17630059 | 0.72 | EGLN2 (0.47) | CYP11B2CYP11B1EGLN2SCN9AHSP90AB1 | |
| SCHEMBL18357080 | 0.72 | KDR (0.53) | CSNK1A1CLK4CYP11B2CYP11B1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |