SCHEMBL3364527

SCHEMBL3364527

N#C/C(=C\c1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4cccc5ccccc45)cc3)s2)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.62
APP P05067 1/20 0.53
CISD1 Q9NZ45 1/20 0.41
KDM4E B2RXH2 1/20 0.41
SLC16A3 O15427 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
SLC16A1 P53985 1/20 0.41
GPR35 Q9HC97 1/20 0.41
EGFR P00533 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7008306 0.93 MAPT (0.51) MAPTCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL3364987 0.90 MAPT (0.79) MAPTAPPKDM4ESLC16A3ALDH1A1
SCHEMBL11936972 0.90 MAPT (0.75) MAPTAPPKDM4ESLC16A3ALDH1A1
SCHEMBL7007760 0.89 MAPT (0.74) MAPTAPPKDM4ESLC16A3ALDH1A1
SCHEMBL7007659 0.88 MAPT (0.78) MAPTAPPCISD1KDM4ESLC16A3
SCHEMBL12294129 0.88 MAPT (0.78) MAPTAPPCISD1KDM4ESLC16A3
SCHEMBL12294131 0.87 MAPT (0.80) MAPTAPPCISD1KDM4ESLC16A3
SCHEMBL11936973 0.87 MAPT (0.73) MAPTAPPKDM4ESLC16A3ALDH1A1
SCHEMBL3364925 0.80 APP (0.54) MAPTAPPALDH1A1
SCHEMBL3364204 0.80 MAPT (0.66) MAPTAPPKDM4ESLC16A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL CRY1, DSG1, CRY2 MAPT 4399/4885APP 2553/4885CISD1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.