Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787062 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HSD17B10L3MBTL1DHFRCHEK1 | |
| SCHEMBL3787572 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HSD17B10L3MBTL1DHFRCHEK1 | |
| SCHEMBL3789866 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HSD17B10L3MBTL1DHFRCYP3A4 | |
| SCHEMBL396194 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HSD17B10L3MBTL1DHFRCYP3A4 | |
| SCHEMBL20344255 | 0.76 | HDAC1 (0.41) | ALDH1A1HSD17B10L3MBTL1CYP3A4TDP1 | |
| SCHEMBL3802241 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10L3MBTL1DHFRCYP3A4 | |
| SCHEMBL394650 | 0.75 | ALOX5AP (0.48) | ALDH1A1HSD17B10L3MBTL1DHFRCYP3A4 | |
| SCHEMBL18504313 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10L3MBTL1DHFRCYP3A4 | |
| SCHEMBL10987129 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10L3MBTL1DHFRCYP3A4 | |
| SCHEMBL19320092 | 0.73 | TDP1 (0.51) | ALDH1A1HSD17B10CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | ALDH1A1 2240/4885HSD17B10 3252/4885L3MBTL1 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.