Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365143 | 0.88 | PDE10A (0.51) | DPP4ALDH1A1HPGDL3MBTL1RAB9A | |
| SCHEMBL3361298 | 0.87 | DPP4 (0.46) | DPP4ALDH1A1HPGDRAB9ACYP1A2 | |
| SCHEMBL3363099 | 0.86 | DPP4 (0.49) | DPP4ALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL3362414 | 0.85 | DPP4 (0.61) | DPP4ALDH1A1HPGDL3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL3361903 | 0.84 | DPP4 (0.62) | DPP4ALDH1A1HPGDL3MBTL1RAB9A | |
| SCHEMBL3362101 | 0.82 | DPP4 (0.67) | DPP4ALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL3362437 | 0.81 | DPP4 (0.45) | DPP4ALDH1A1L3MBTL1TSHRHSD17B10 | |
| SCHEMBL3365615 | 0.80 | DPP4 (0.41) | DPP4ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL3361307 | 0.80 | DPP4 (0.46) | DPP4ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL3359830 | 0.79 | NAMPT (0.44) | DPP4ALDH1A1HPGDL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |