Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363099 | 0.86 | DPP4 (0.49) | DPP4ABCB1GFERHSD17B10L3MBTL1 | |
| SCHEMBL3360962 | 0.84 | DPP4 (0.41) | DPP4ABCB1GFERHSD17B10L3MBTL1 | |
| SCHEMBL3360966 | 0.83 | DPP4 (0.41) | DPP4ABCB1GFERHSD17B10L3MBTL1 | |
| SCHEMBL3363973 | 0.83 | DPP4 (0.43) | DPP4MAPKAPK2CTSL | |
| SCHEMBL3362101 | 0.83 | DPP4 (0.67) | DPP4ALDH1A1NPSR1 | |
| SCHEMBL3362011 | 0.83 | DPP4 (0.40) | DPP4ABCB1GFERHSD17B10L3MBTL1 | |
| SCHEMBL3361298 | 0.82 | DPP4 (0.46) | DPP4ABCB1HSD17B10ALDH1A1 | |
| SCHEMBL3365202 | 0.81 | DPP4 (0.44) | DPP4HSD17B10L3MBTL1ALDH1A1TSHR | |
| SCHEMBL3361307 | 0.81 | DPP4 (0.46) | DPP4ABCB1GFERHSD17B10L3MBTL1 | |
| SCHEMBL3362364 | 0.78 | ABCB1 (0.40) | DPP4ABCB1HSD17B10DYRK1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |