SCHEMBL336549

SCHEMBL336549

C=CC(=O)NC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
CA12 O43570 3/20 0.38
MMP2 P08253 2/20 0.38
CA14 Q9ULX7 1/20 0.38
CYP2C19 P33261 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA9 Q16790 2/20 0.30
TGM2 P21980 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7141232 0.79 TSHR (0.48) TSHRCYP2C19ALDH1A1MAPK1TDP1
SCHEMBL1564157 0.77 TSHR (0.58) TSHRCA12MMP2CYP2C19ALDH1A1
SCHEMBL5489505 0.77 TSHR (0.46) TSHRCYP2C19ALDH1A1MAPK1TDP1
Phosphoric Acid SCHEMBL10755154 0.74 TSHR (0.82) TSHRCA12MMP2CYP2C19ALDH1A1
SCHEMBL491509 0.74 TSHR (0.54) TSHRCA12MMP2CYP2C19ALDH1A1
SCHEMBL5177219 0.73 TSHR (0.52) TSHRCA12MMP2CYP2C19ALDH1A1
SCHEMBL8384172 0.73 TSHR (0.47) TSHRCA12MMP2CYP2C19ALDH1A1
SCHEMBL2554848 0.70 MMP1 (0.44) TSHRCA12MMP2CYP2C19ALDH1A1
SCHEMBL337892 0.70 TSHR (0.44) TSHRCA12MMP2ALDH1A1MAPK1
SCHEMBL18297791 0.70 TSHR (0.54) TSHRCA12MMP2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097126-B2 Aqueous composition and use thereof for paper production BASF SE (DE) 2012-01-17 US claimed
EP-1654419-B1 AQUEOUS COMPOSITION AND USE THEREOF FOR PAPER PRODUCTION BASF AG (DE) 2006-11-08 EP claimed
US-20060037725-A1 Aqueous composition and use thereof for paper production BASF AKTIENGESELLSCHAFT (DE) 2006-02-23 US claimed
US-20060024262-A1 Aqueous composition and use thereof for paper production BASF AKTIENGESELLSCHAFT (DE) 2006-02-02 US claimed
WO-2024132736-A1 PROCESS FOR MANUFACTURING A MULTI-LAYER PAPER OR CARDBOARD BASF SE (DE) 2024-06-27 WO disclosed
EP-3697964-B1 METHOD FOR THE PREPARATION OF SINGLE LAYER OR MULTI-LAYER PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-06-26 EP disclosed
EP-3697963-B1 METHOD FOR PRODUCING MULTIPLE PLY PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-06-26 EP disclosed
US-12018113-B2 Method for the hydrolysis of a polymer SOLENIS TECHNOLOGIES, L.P. (US) 2024-06-25 US disclosed
EP-3695051-B1 METHOD FOR FORMING PAPER OR CARDBOARD SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-06-19 EP disclosed
EP-4363663-A1 N-VINYLLACTAM-CONTAINING POLYMERS FOR PAPERMAKING Solenis Technologies, L.P. (US) 2024-05-08 EP disclosed
US-11680371-B2 Method for producing multi-layer paper SOLENIS TECHNOLOGIES, L.P. (US) 2023-06-20 US disclosed
CN-113039223-B Method for hydrolyzing polymer 索理思科技开曼公司(KY) 2023-01-13 CN disclosed
EP-1716836-A1 Surface-modified fillers Ivoclar Vivadent AG (LI) 2006-11-02 EP disclosed
EP-1654419-A1 AQUEOUS COMPOSITION AND USE THEREOF FOR PAPER PRODUCTION BASF AKTIENGESELLSCHAFT (DE) 2006-05-10 EP disclosed
US-20060037725-A1 Aqueous composition and use thereof for paper production BASF AKTIENGESELLSCHAFT (DE) 2006-02-23 US disclosed
US-20060024262-A1 Aqueous composition and use thereof for paper production BASF AKTIENGESELLSCHAFT (DE) 2006-02-02 US disclosed
WO-2005012637-A1 AQUEOUS COMPOSITION AND USE THEREOF FOR PAPER PRODUCTION BASF AKTIENGESELLSCHAFT (DE) 2005-02-10 WO disclosed
EP-0909761-B1 Hydrolysis-stable and polymerizable acryl phosphonic acids IVOCLAR VIVADENT AG (LI) 2003-04-02 EP disclosed
US-6172131-B1 MADE BY REACTING AN ALPHA-HALOMETHACRYLIC ACID ESTER WITH PROTECTED MONO- OR DIFUNCTIONAL PHOSPHONIC ACID ESTERS; USE AS COMPONENT OF DENTAL ADHESIVES DUE TO THEIR ADHESION-PROMOTING PROPERTIES IVOCLAR AG 2001-01-09 US disclosed
EP-0909761-A1 Hydrolysis-stable and polymerizable acryl phosphonic acids IVOCLAR AG (LI) 1999-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060024262-A1 Aqueous composition and use thereof for paper production CHMP4B, AQP1, IL17A TSHR 4840/4885CA12 543/4885MMP2 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.