SCHEMBL491509

SCHEMBL491509

C=CC(=O)NC(C(C)C)P(=O)(O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MMP1 P03956 5/20 0.34
MMP2 P08253 5/20 0.34
MMP9 P14780 4/20 0.34
MMP8 P22894 4/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
CYP2C19 P33261 1/20 0.33
LAP3 P28838 1/20 0.32
MMP3 P08254 4/20 0.31
MMP7 P09237 3/20 0.31
MMP13 P45452 3/20 0.31
MMP14 P50281 3/20 0.31
ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1564157 0.79 TSHR (0.58) TSHRALDH1A1MAPK1TDP1MMP1
Phosphoric Acid SCHEMBL10755154 0.77 TSHR (0.82) TSHRALDH1A1MAPK1TDP1MMP1
SCHEMBL5177219 0.74 TSHR (0.52) TSHRALDH1A1MAPK1TDP1MMP1
SCHEMBL336549 0.74 TSHR (0.50) TSHRALDH1A1MAPK1TDP1MMP1
SCHEMBL9797754 0.74 MMP2 (0.39) ALDH1A1MMP1MMP2MMP9MMP8
SCHEMBL7141232 0.72 TSHR (0.48) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL18297791 0.72 TSHR (0.54) TSHRALDH1A1MAPK1TDP1MMP1
SCHEMBL94755 0.72 TGFBR1 (0.40) MMP1MMP2MMP9MMP8CA12
SCHEMBL1907642 0.72 TSHR (0.65) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL29244359 0.72 TSHR (0.65) TSHRALDH1A1MAPK1TDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024094892-A1 TITANATE SCALE INHIBITION IN A SINGLE STREAM BAYER PROCESS CYTEC INDUSTRIES INC. (US) 2024-05-10 WO claimed
JP-2001523751-A 2001-11-27 JP claimed
EP-1029009-A1 PREPARATIONS MADE OF PIGMENTS AND RESIN CONTAINING PHOSPHONATE BASF AKTIENGESELLSCHAFT (DE) 2000-08-23 EP claimed
WO-1999025780-A1 PREPARATIONS MADE OF PIGMENTS AND RESIN CONTAINING PHOSPHONATE BASF AKTIENGESELLSCHAFT (DE) 1999-05-27 WO claimed
WO-2024094892-A1 TITANATE SCALE INHIBITION IN A SINGLE STREAM BAYER PROCESS CYTEC INDUSTRIES INC. (US) 2024-05-10 WO disclosed
US-20230416602-A1 FLUORESCENT POLYMERS AND SOLUTIONS THEREOF FOR SCALE CONTROL IN AQUEOUS SYSTEMS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-12-28 US disclosed
EP-4247899-A1 FLUORESCENT POLYMERS AND SOLUTIONS THEREOF FOR SCALE CONTROL IN AQUEOUS SYSTEMS Nouryon Chemicals International B.V. (NL) 2023-09-27 EP disclosed
CN-116710524-A Fluorescent polymers and solutions thereof for scale control in aqueous systems 诺力昂化学品国际有限公司 2023-09-05 CN disclosed
US-11542187-B2 Composition and method for controlling scale in industrial water systems NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-01-03 US disclosed
US-20220228054-A1 FLUORESCENT NAPHTHALIMIDE POLYMERS AND SOLUTIONS THEREOF FOR SCALE CONTROL IN AQUEOUS SYSTEMS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-07-21 US disclosed
US-20220227648-A1 METHOD OF CONTROLLING CARBONATE SCALE IN AQUEOUS SYSTEMS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-07-21 US disclosed
CN-112867920-B Method for controlling scale formation in water systems 诺力昂化学品国际有限公司 2022-07-15 CN disclosed
EP-0909761-A1 Hydrolysis-stable and polymerizable acryl phosphonic acids IVOCLAR AG (LI) 1999-04-21 EP disclosed
US-5753404-A USEFUL FOR PRODUCTION OF PLANOGRAPHIC PRINTING PLATE AGFA-GEVAERT AG (DE) 1998-05-19 US disclosed
EP-0607388-B1 USE OF GRAFT POLYMERS FOR STUFFING AND FULLING LEATHERS AND FUR PELTS BASF AG (DE) 1997-10-08 EP disclosed
US-5620748-A Use of graft polymers for fatliquoring and filling leather and fur skins BASF AKTIENGESELLSCHAFT (DE) 1997-04-15 US disclosed
EP-0710889-A2 Light-sensitive recording material HOECHST AKTIENGESELLSCHAFT (DE) 1996-05-08 EP disclosed
EP-0607388-A1 USE OF GRAFT POLYMERS FOR STUFFING AND FULLING LEATHERS AND FUR PELTS. BASF AG (DE) 1994-07-27 EP disclosed
WO-1994002650-A1 USE OF GRAFT POLYMERS FOR STUFFING AND FULLING LEATHERS AND FUR PELTS BASF AKTIENGESELLSCHAFT (DE) 1994-02-03 WO disclosed
EP-0446469-A1 Flame retardant polyacrylnitrile-(Co)-polymers containing phosphorus - containing derivatives of phenols BAYER AG (DE) 1991-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230416602-A1 FLUORESCENT POLYMERS AND SOLUTIONS THEREOF FOR SCALE CONTROL IN AQUEOUS SYSTEMS FGB, F10, TFPI TSHR 4507/4885ALDH1A1 2733/4885MAPK1 3530/4885
US-11542187-B2 Composition and method for controlling scale in industrial water systems TP53, PHOSPHO1, PPIP5K2 TSHR 4415/4885ALDH1A1 4375/4885MAPK1 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.