Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426052 | 0.84 | KMO (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19RAB9A | |
| SCHEMBL13425542 | 0.81 | CLK4 (0.41) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3399321 | 0.77 | FFAR1 (0.42) | SMN1; SMN2RAB9ANPC1NR1H2MEN1 | |
| SCHEMBL3400178 | 0.73 | CCNT1 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL8888588 | 0.72 | RAB9A (0.65) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13426106 | 0.72 | FYN (0.46) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13425533 | 0.70 | KCNH2 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL13425685 | 0.69 | MAPT (0.41) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13426803 | 0.67 | CLK4 (0.41) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13425732 | 0.67 | CLK4 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |