Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.40 |
| ▸ | KDM4A | O75164 | 3/20 | 0.40 |
| ▸ | KDM6B | O15054 | 2/20 | 0.40 |
| ▸ | TET3 | O43151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505808 | 0.78 | KDM4E (0.57) | KDM4ELMNAKMT2AMEN1TDP1 | |
| SCHEMBL3369832 | 0.75 | KDM4E (0.50) | KDM4ELMNAKMT2AMEN1TDP1 | |
| SCHEMBL696116 | 0.74 | XDH (0.50) | KDM4ELMNAKMT2AMEN1TDP1 | |
| SCHEMBL3371440 | 0.73 | KDM4E (0.40) | KDM4ELMNATDP1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL7968706 | 0.73 | XDH (0.49) | KDM4ELMNAKMT2AMEN1TDP1 | |
| SCHEMBL9823339 | 0.72 | EGLN1 (0.53) | KDM4ELMNATDP1L3MBTL1NAPRT | |
| SCHEMBL6873637 | 0.71 | KDM4E (0.56) | KDM4ELMNAKMT2AMEN1TDP1 | |
| SCHEMBL3368447 | 0.71 | KDM4C (0.61) | KDM4EKDM3AKDM5AALDH1A1EGLN1 | |
| SCHEMBL2162964 | 0.71 | CYP1A2 (0.57) | KDM4ELMNAKMT2ATDP1ALOX15 | |
| SCHEMBL22815116 | 0.70 | KDM4E (0.48) | KDM4ELMNAKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |