Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792368 | 0.84 | KDM4E (0.50) | KDM4EHPGDSALDH1A1PTGER1ACHE | |
| SCHEMBL27740378 | 0.80 | ACHE (0.55) | KDM4EHPGDSALDH1A1PTGER1ACHE | |
| SCHEMBL9823475 | 0.80 | RAB9A (0.54) | EGLN1KDM4EALDH1A1LMNACYP19A1 | |
| SCHEMBL3366715 | 0.80 | EGLN1 (0.69) | EGLN1TLR7 | |
| SCHEMBL1995375 | 0.79 | HPGDS (0.59) | KDM4EHPGDSALDH1A1ACHETLR7 | |
| SCHEMBL3368044 | 0.78 | EGLN1 (0.69) | EGLN1KDM4EALDH1A1LMNA | |
| SCHEMBL9823334 | 0.78 | HTR2B (0.73) | KDM4EHPGDSALDH1A1PTGER1ACHE | |
| SCHEMBL22940438 | 0.76 | PDE10A (0.54) | EGLN1KDM4EALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL28780113 | 0.76 | ACHE (0.54) | KDM4EHPGDSALDH1A1ACHEHTR2B | |
| SCHEMBL9823411 | 0.75 | TLR7 (0.43) | EGLN1TLR7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |