Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399384 | 0.78 | LCK (0.46) | BACE1JAK3PLA2G7NPC1RAB9A | |
| SCHEMBL29939240 | 0.78 | CYP11B1 (0.51) | BACE1ALOX5APFEN1DYRK1A | |
| SCHEMBL31226272 | 0.78 | USP7 (0.53) | USP7CYP2A6NPC1RAB9AALDH1A1 | |
| SCHEMBL4771 | 0.78 | CYP2A6 (0.47) | USP7CYP2A6BACE1NPC1RAB9A | |
| SCHEMBL13778315 | 0.78 | CYP2A6 (0.47) | USP7CYP2A6PLA2G7NPC1RAB9A | |
| SCHEMBL16702215 | 0.78 | CYP11B1 (0.51) | BACE1ALOX5APFEN1DYRK1A | |
| SCHEMBL3363386 | 0.77 | CLK1 (0.46) | NPC1RAB9ADYRK1A | |
| SCHEMBL3363485 | 0.75 | CYP2A6 (0.58) | CYP2A6BACE1JAK2JAK1TYK2 | |
| SCHEMBL558114 | 0.74 | DYRK1B (0.54) | ALDH1A1LMNADYRK1BDYRK1AMAPT | |
| SCHEMBL2009521 | 0.74 | CYP2A6 (0.56) | CYP2A6NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |