Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366249 | 0.77 | USP7 (0.49) | NPC1RAB9ADYRK1A | |
| SCHEMBL22452543 | 0.77 | TAAR1 (0.47) | CLK1NISCHCYP3A4NPC1RAB9A | |
| SCHEMBL21022227 | 0.76 | MAOA (0.44) | CLK1NISCHCYP3A4HSD11B1GRM2 | |
| SCHEMBL4503767 | 0.75 | TDO2 (0.54) | CLK1TDO2 | |
| SCHEMBL27898901 | 0.74 | CYP11B2 (0.56) | CYP11B1CYP11B2NTRK1TDO2IRAK4 | |
| SCHEMBL3383277 | 0.73 | MAPK14 (0.56) | CYP11B1CYP11B2NISCH | |
| SCHEMBL27699623 | 0.72 | NPC1 (0.40) | CLK1NISCHCYP17A1NPC1RAB9A | |
| SCHEMBL1262207 | 0.72 | GRM2 (0.48) | CLK1NISCHNPC1RAB9AHSD11B1 | |
| SCHEMBL31067069 | 0.72 | GRM2 (0.48) | CLK1NISCHNPC1RAB9AHSD11B1 | |
| SCHEMBL16702215 | 0.70 | CYP11B1 (0.51) | CYP11B1CYP11B2IRAK4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |