Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HCN1 | O60741 | 1/20 | 0.40 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16674268 | 0.85 | IRAK4 (0.68) | IRAK4ALDH1A1ACHEIDO1TDO2 | |
| SCHEMBL3366337 | 0.82 | HTT (0.45) | IRAK4ALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL3364578 | 0.81 | CTSD (0.53) | ALDH1A1KCNK3KCNK9HPGD | |
| SCHEMBL7088362 | 0.81 | IRAK4 (0.72) | IRAK4ALDH1A1ACHEIDO1TDO2 | |
| SCHEMBL2094692 | 0.81 | IRAK4 (0.72) | IRAK4ALDH1A1ACHEIDO1TDO2 | |
| SCHEMBL28293902 | 0.79 | IRAK4 (0.70) | IRAK4ALDH1A1ACHEIDO1TDO2 | |
| SCHEMBL104892 | 0.79 | IRAK4 (0.70) | IRAK4ALDH1A1ACHEIDO1TDO2 | |
| SCHEMBL2818437 | 0.78 | IRAK4 (0.58) | IRAK4ALDH1A1ACHEIDO1TDO2 | |
| SCHEMBL2103513 | 0.78 | IRAK4 (1.00) | IRAK4ALDH1A1ACHEIDO1TDO2 | |
| Bicarbonate SCHEMBL21811920 | 0.78 | IRAK4 (0.68) | IRAK4ALDH1A1ACHEIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |