Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438201 | 0.82 | SMN1; SMN2 (0.50) | HTTALDH1A1CYP11B1SMN1; SMN2NPC1 | |
| SCHEMBL3366372 | 0.82 | IRAK4 (0.64) | ALDH1A1LMNAKMT2AKDM4EIRAK4 | |
| SCHEMBL29059114 | 0.81 | GAA (0.44) | HTTALDH1A1CYP11B1SMN1; SMN2NPC1 | |
| SCHEMBL11212937 | 0.81 | HTT (0.49) | HTTALDH1A1CYP11B1SMN1; SMN2NPC1 | |
| SCHEMBL975946 | 0.79 | KDM4E (0.55) | HTTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11896596 | 0.78 | LMNA (0.49) | HTTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2301384 | 0.78 | ALDH1A1 (0.48) | HTTALDH1A1CYP11B1SMN1; SMN2NPC1 | |
| SCHEMBL1286684 | 0.78 | IRAK4 (0.53) | HTTALDH1A1CYP11B1SMN1; SMN2NPC1 | |
| SCHEMBL3364578 | 0.78 | CTSD (0.53) | HTTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29930602 | 0.78 | ALDH1A1 (0.48) | HTTALDH1A1CYP11B1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |