Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114448 | 0.98 | CYP3A4 (0.54) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL564739 | 0.98 | CYP3A4 (0.54) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL6066015 | 0.88 | CYP2A6 (0.70) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL2319993 | 0.81 | TDP1 (0.51) | TSHRALDH1A1TDP1NCOA1NCOA3 | |
| SCHEMBL12266516 | 0.78 | CYP2A6 (0.56) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL2851573 | 0.77 | NCF1 (0.37) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL14931471 | 0.77 | ALDH1A1 (0.59) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL29508482 | 0.77 | ALDH1A1 (0.59) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL8404538 | 0.77 | CYP2A6 (0.59) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL28196297 | 0.75 | CYP3A4 (0.56) | CYP3A4TSHRALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097756-B2 | Process for producing carboxylic acid anhydrides | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2012-01-17 | — | — | US | claimed |
| US-20100145098-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ANHYDRIDES | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2010-06-10 | — | — | US | claimed |
| US-8097756-B2 | Process for producing carboxylic acid anhydrides | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2012-01-17 | — | — | US | disclosed |
| US-20100145098-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ANHYDRIDES | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145098-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ANHYDRIDES | CA4, CA9, CA7 | CYP3A4 102/4885TSHR 2511/4885ALDH1A1 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.