Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114448 | 0.78 | CYP3A4 (0.54) | NCF1CYP2A6ALDH1A1KDM4ETDP1 | |
| SCHEMBL564343 | 0.78 | ALDH1A1 (0.51) | NCF1ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL564739 | 0.78 | CYP3A4 (0.54) | NCF1CYP2A6ALDH1A1KDM4ETDP1 | |
| Iodide SCHEMBL336638 | 0.77 | CYP3A4 (0.52) | NCF1CYP2A6ALDH1A1KDM4ETDP1 | |
| SCHEMBL3344492 | 0.75 | NOS3 (0.48) | CYP2A6ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL6066015 | 0.73 | CYP2A6 (0.70) | NCF1CYP2A6ALDH1A1KDM4ETDP1 | |
| SCHEMBL564279 | 0.72 | NCF1 (0.60) | NCF1ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL3846386 | 0.72 | ALDH1A1 (0.59) | CYP2A6ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL29401886 | 0.72 | ALDH1A1 (0.59) | CYP2A6ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL10078327 | 0.70 | CYP2A6 (0.47) | NCF1CYP2A6ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142503-A2 | PROCESS FOR THE MANUFACTURE FOR NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND INTERMEDIATES THEREOF | Intendis GmbH (DE) | 2010-01-13 | — | — | EP | claimed |
| WO-2008128750-A2 | PROCESS FOR THE MANUFACTURE FOR NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND INTERMEDIATES THEREOF | INTENDIS GMBH (DE) | 2008-10-30 | — | — | WO | claimed |