Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.56 |
| ▸ | OXTR | P30559 | 2/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399456 | 0.85 | OXTR (0.56) | OXTRMAPTKMT2AMEN1AVPR1A | |
| SCHEMBL3369096 | 0.76 | OXTR (0.74) | HCRTR1HCRTR2OXTRMAPTKMT2A | |
| SCHEMBL3366536 | 0.76 | OXTR (0.74) | HCRTR1HCRTR2OXTRMAPTKMT2A | |
| SCHEMBL3367233 | 0.75 | TP53 (0.59) | TP53HCRTR1HCRTR2OXTRPTGER1 | |
| SCHEMBL16557491 | 0.72 | MAPT (0.66) | TP53HCRTR1HCRTR2OXTRMAPT | |
| SCHEMBL3366502 | 0.72 | POLB (0.51) | TP53HCRTR1HCRTR2OXTRPTGER1 | |
| SCHEMBL3366498 | 0.72 | POLB (0.51) | TP53HCRTR1HCRTR2OXTRPTGER1 | |
| SCHEMBL14107550 | 0.71 | PKM (0.61) | TP53HCRTR1HCRTR2MAPTKMT2A | |
| SCHEMBL3367782 | 0.71 | SMN1; SMN2 (0.51) | OXTRPTGER1MAPTPKMAVPR1A | |
| SCHEMBL3366546 | 0.70 | TP53 (0.49) | TP53HCRTR1HCRTR2OXTRPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |