Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366540 | 0.85 | TP53 (0.56) | OXTRMAPTALDH1A1AVPR1AGAA | |
| SCHEMBL3367782 | 0.81 | SMN1; SMN2 (0.51) | OXTRMAPTALDH1A1HPGDAVPR1A | |
| SCHEMBL24279588 | 0.75 | OXTR (0.57) | OXTRMAPTALDH1A1HPGDAVPR1A | |
| SCHEMBL3399452 | 0.72 | OXTR (1.00) | OXTRMAPTALDH1A1HPGDAVPR1A | |
| SCHEMBL1630305 | 0.72 | KEAP1 (0.71) | OXTRMAPTMEN1KMT2A | |
| SCHEMBL3367904 | 0.71 | OXTR (1.00) | OXTRMAPTHPGDAVPR1AGAA | |
| SCHEMBL10956866 | 0.69 | NR1I2 (0.64) | OXTRMAPTALDH1A1AVPR1AHTT | |
| SCHEMBL16557466 | 0.68 | KMT2A (0.67) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2704489 | 0.68 | KEAP1 (0.58) | OXTRGAAMEN1KMT2AHTT | |
| SCHEMBL1630148 | 0.68 | HCRTR2 (0.61) | OXTRALDH1A1AVPR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |