Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20866604 | 0.98 | ALDH1A1 (0.53) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL8312391 | 0.96 | NISCH (0.51) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL7905159 | 0.83 | BCL2L1 (0.54) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL12101466 | 0.83 | MEN1 (0.56) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL18906788 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL19112709 | 0.80 | NISCH (0.49) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL7262779 | 0.79 | SIGMAR1 (0.53) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL12883500 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL8166642 | 0.79 | HTT (0.58) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL7961751 | 0.78 | SIGMAR1 (0.51) | ALDH1A1LMNAMEN1KMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303586-A1 | INHIBITORS OF KRAS G12C | ARAXES PHARMA LLC (US) | 2023-09-28 | — | — | US | disclosed |
| EP-3423435-B1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | UNIV VANDERBILT (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2023125627-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | LYNK PHARMACEUTICALS CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |
| WO-2022036297-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| EP-3822270-A1 | NOVEL HETEROCYCLE DERIVATIVE | JW Pharmaceutical Corporation (KR) | 2021-05-19 | — | — | EP | disclosed |
| US-10254645-B2 | Photosensitive resin composition, method for producing cured film, cured film, liquid crystal display device, organic electroluminescent display device, and touch panel | FUJIFILM CORPORATION (JP) | 2019-04-09 | — | — | US | disclosed |
| US-20170168391-A1 | PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED FILM, CURED FILM, LIQUID CRYSTAL DISPLAY DEVICE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND TOUCH PANEL | FUJIFILM CORPORATION (JP) | 2017-06-15 | — | — | US | disclosed |
| US-20170168391-A1 | PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED FILM, CURED FILM, LIQUID CRYSTAL DISPLAY DEVICE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND TOUCH PANEL | FUJIFILM CORPORATION (JP) | 2017-06-15 | — | — | US | disclosed |
| US-20170152229-A1 | TETRAHYDROISOQUINOLINONE DERIVATIVES AND THEIR USE IN THE INHIBITION OF THE HSP70 PROTEIN | JULIUS-MAXIMILIANS-UNIVERSITAET WUERZBURG (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20140031368-A1 | SELECTIVE HDAC INHIBITORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-01-30 | — | — | US | disclosed |
| US-20070049570-A1 | Quinoline derivatives as phosphodiesterase inhibitors | DEAN ANTHONY W | 2007-03-01 | — | — | US | disclosed |
| US-6878510-B2 | Method of processing silver halide photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20050032008-A1 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. | 2005-02-10 | — | — | US | disclosed |
| US-6844146-B2 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-01-18 | — | — | US | disclosed |
| WO-2004103998-A1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-02 | — | — | WO | disclosed |
| US-20040058282-A1 | Method of processing silver halide photosensitive material | FUJI PHOTO FILM CO., LTD. | 2004-03-25 | — | — | US | disclosed |
| US-6696215-B2 | HIGH CONTRAST AND PHOTOSENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 2004-02-24 | — | — | US | disclosed |
| US-20040018458-A1 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-20030232272-A1 | Silver halide photographic light sensitive material | FUJIFILM CORPORATION (JP) | 2003-12-18 | — | — | US | disclosed |
| US-20030198905-A1 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152229-A1 | TETRAHYDROISOQUINOLINONE DERIVATIVES AND THEIR USE IN THE INHIBITION OF THE HSP70 PROTEIN | HSPH1, HSP90AB1, HSP90AB2P | ALDH1A1 2256/4885LMNA 4452/4885MEN1 4303/4885 |
| US-20140031368-A1 | SELECTIVE HDAC INHIBITORS | HDAC1, HDAC11, HDAC3 | ALDH1A1 1489/4885LMNA 1269/4885MEN1 2678/4885 |
| US-20070049570-A1 | Quinoline derivatives as phosphodiesterase inhibitors | PDE3B, PDE4B, PDE4A | ALDH1A1 623/4885LMNA 2744/4885MEN1 2927/4885 |
| US-20230303586-A1 | INHIBITORS OF KRAS G12C | KRAS, NRAS, HRAS | ALDH1A1 4178/4885LMNA 407/4885MEN1 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.