Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 17/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 14/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 14/20 | 0.42 |
| ▸ | GABRP | O00591 | 11/20 | 0.42 |
| ▸ | GABRD | O14764 | 11/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 11/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 11/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 11/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 11/20 | 0.42 |
| ▸ | GABRE | P78334 | 11/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 11/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 11/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 11/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 11/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366234 | 0.92 | GABRB3 (0.42) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL3963848 | 0.89 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL4082183 | 0.86 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055815 | 0.86 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL711450 | 0.85 | GABRB3 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL921378 | 0.83 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055924 | 0.83 | GABRB3 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9010483 | 0.80 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055593 | 0.79 | GABRB3 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055750 | 0.79 | GABRB3 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730115-B1 | 5-AMINOALKYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS | MERIAL LTD (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1730115-A1 | 5-AMINOALKYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS | Merial Ltd. (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005090312-A1 | 5-AMINOALKYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS | MERIAL LTD. (US) | 2005-09-29 | — | — | WO | disclosed |