Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 20/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.47 |
| ▸ | GABRP | O00591 | 18/20 | 0.47 |
| ▸ | GABRD | O14764 | 18/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 18/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 18/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 18/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 18/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 18/20 | 0.47 |
| ▸ | GABRE | P78334 | 18/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 18/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 18/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 18/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 18/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963848 | 0.90 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055815 | 0.87 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL3367279 | 0.86 | GABRB3 (0.42) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL3366234 | 0.86 | GABRB3 (0.42) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL921378 | 0.85 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL711450 | 0.83 | GABRB3 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055924 | 0.83 | GABRB3 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9010483 | 0.82 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055593 | 0.81 | GABRB3 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055750 | 0.80 | GABRB3 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517877-B2 | 5-substituted-alkylaminopyrazole derivatives as pesticides | MERIAL LIMITED (US) | 2009-04-14 | — | — | US | disclosed |
| US-20050182048-A1 | 5-substituted-alkylaminopyrazole derivatives as pesticides | BAYER CORO SCIENCE S.A. (FR) | 2005-08-18 | — | — | US | disclosed |
| EP-1483246-A1 | 5-SUBSTITUTED-ALKYLAMINOPYRAZOLE DERIVATIVES AS PESTICIDES | Bayer CropScience S.A. (FR) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074493-A1 | 5-SUBSTITUTED-ALKYLAMINOPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE S.A. (FR) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182048-A1 | 5-substituted-alkylaminopyrazole derivatives as pesticides | DDT, PTMS, CYP3A5 | GABRB3 497/4885GABRA2 474/4885GABRB2 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.