Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769868 | 0.85 | SLC6A5 (0.62) | SLC6A5EPHX2 | |
| SCHEMBL30349 | 0.85 | SLC6A5 (0.62) | SLC6A5EPHX2 | |
| SCHEMBL25711820 | 0.85 | SLC6A5 (0.62) | SLC6A5EPHX2 | |
| SCHEMBL31348788 | 0.85 | SLC6A5 (0.62) | SLC6A5EPHX2 | |
| SCHEMBL769870 | 0.85 | SLC6A5 (0.62) | SLC6A5EPHX2 | |
| SCHEMBL9800921 | 0.85 | SLC6A5 (0.62) | SLC6A5EPHX2 | |
| SCHEMBL3096362 | 0.85 | SLC6A5 (0.62) | SLC6A5EPHX2 | |
| SCHEMBL2185171 | 0.84 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2 | |
| SCHEMBL19468503 | 0.84 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2 | |
| SCHEMBL76613 | 0.84 | EPHX1 (0.67) | EPHX1ZDHHC20ZDHHC2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556682-B8 | IP3 PROTEIN BINDING ASSAY | DISCOVERX CORP (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-1556682-B1 | IP sb 3 /sb PROTEIN BINDING ASSAY | DISCOVERX CORP (US) | 2009-10-07 | — | — | EP | disclosed |
| EP-1556682-A4 | IP sb 3 /sb PROTEIN BINDING ASSAY | DISCOVERX INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1556682-A2 | IP sb 3 /sb PROTEIN BINDING ASSAY | Discoverx, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| US-20040106158-A1 | IP3 protein binding assay | DISCOVERX, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2004038369-A2 | IP3 PROTEIN BINDING ASSAY | DISCOVERX, INC. (US) | 2004-05-06 | — | — | WO | disclosed |