SCHEMBL4247405

SCHEMBL4247405

O=P(Cc1ccccc1)(OCc1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
HPGD P15428 1/20 0.47
CETP P11597 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
AOX1 Q06278 1/20 0.40
KYNU Q16719 1/20 0.40
SRC P12931 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
IDO1 P14902 1/20 0.39
PDPK1 O15530 1/20 0.39
MTOR P42345 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7916451 0.83 AOX1 (0.58) HPGDMEN1KMT2AALDH1A1AOX1
SCHEMBL11509131 0.80 TSHR (0.55) TSHRCETPKMT2AKDM4EALDH1A1
SCHEMBL9761734 0.78 MEN1 (0.51) TSHRHPGDMEN1KMT2AAOX1
SCHEMBL5400948 0.78 TSHR (0.61) TSHRCETPMEN1KMT2AALDH1A1
SCHEMBL5850148 0.78 TSHR (0.61) TSHRHPGDCETPALDH1A1SRC
SCHEMBL389123 0.78 TSHR (0.61) TSHRCETPMEN1KMT2AKDM4E
SCHEMBL8412588 0.78 MEN1 (0.49) CETPMEN1KMT2AAOX1
SCHEMBL1967085 0.77 L3MBTL1 (0.53) HPGDMEN1KMT2AKDM4ESRC
SCHEMBL3069900 0.76 TSHR (0.59) TSHRHPGDCETPALDH1A1SRC
SCHEMBL3367720 0.76 TSHR (0.58) TSHRHPGDCETPKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903195-A Method for preparing (2-oxo-2-arylethyl) (phenyl) phosphonate alkyl ester compound 湖南理工学院 2024-04-19 CN claimed
CN-117903195-A Method for preparing (2-oxo-2-arylethyl) (phenyl) phosphonate alkyl ester compound 湖南理工学院 2024-04-19 CN disclosed
EP-1876193-B1 PROCESS FOR PRODUCING POLYOXYMETHYLENE COPOLYMER MITSUBISHI GAS CHEMICAL CO (JP) 2013-12-25 EP disclosed
US-7897672-B2 Process for producing polyoxymethylene copolymer MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-03-01 US disclosed
US-20090062503-A1 Process for Producing Polyoxymethylene Copolymer MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-03-05 US disclosed
EP-1876193-A1 PROCESS FOR PRODUCING POLYOXYMETHYLENE COPOLYMER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-01-09 EP disclosed