Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643240 | 1.00 | MAPT (0.62) | MAPTPOLBKDM4EHTTALDH1A1 | |
| SCHEMBL3364018 | 0.90 | MAPT (0.62) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL3364021 | 0.90 | MAPT (0.62) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL3367779 | 0.80 | OXTR (0.71) | MAPTPOLBKDM4EHTTALDH1A1 | |
| SCHEMBL21647692 | 0.72 | SMN1; SMN2 (0.60) | MAPTHTTALDH1A1PTGER1MEN1 | |
| SCHEMBL3367782 | 0.71 | SMN1; SMN2 (0.51) | MAPTKDM4EHTTALDH1A1HPGD | |
| SCHEMBL12768012 | 0.71 | LMNA (0.57) | MAPTKDM4EHTTHPGDPTGER1 | |
| SCHEMBL5643243 | 0.71 | ALDH1A1 (0.43) | MAPTKDM4EHTTALDH1A1HPGD | |
| SCHEMBL398861 | 0.71 | KEAP1 (0.70) | MAPTMEN1KMT2A | |
| SCHEMBL3366536 | 0.70 | OXTR (0.74) | MAPTPOLBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |